Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of numerous myeloma. Its synthesis or research is vital for ensuring the purity and safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the treatment of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular types of cancer, including chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their examine is significant for optimizing the manufacturing process and guaranteeing superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to take care of breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the cure of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the CAS NO. 571188-59-5 synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and smaller cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have different programs, together with antiviral Houses.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for style 2 diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of assorted gluconic acid derivatives, which can be Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication employed to control 1 form 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).